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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a37a33cba0585583666fcf24e0998348d47c0c1a3e6796e7b56db8e58117820c' 
  AND token = 'V2eNdO1/CP5T5Gjpw079a++9pGSGc14yvN8FSTzpm1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}