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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dad6c517548d1db077a79ab8e517bce2876f56ada62c8ad2f198b5f5b26cda04' 
  AND token = '+QKtWZ8LL3QHcroQ4n2uvg0RMkuxCks2iqhmAIdUAdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}