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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7323f51439a7950de27fa11f110f55f5b171ed26c31fb6380ba992e271c55b16' 
  AND token = 'VPteIjYDsbsiv0kD4LT2fBfETjdeGB4oPyfMu8lp1KE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}