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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4083a4065bea957208f88e27292f4c194d6182988518f2cc865b5a0939abc675' 
  AND token = 'EHm2yc/ue37PnheiPbNJc9zvxxFwyw7ehxvh5DETAcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}