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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3227d1f175f83b92aca503931e430bf857d235def560b14dff28d98b74e976be' 
  AND token = 'VubPBGMsKS3MX24OdQtUDlbOgspsQ0GNIe8Jlt9vK2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}