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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f11663144c2a9b1c62083f192719ccd15c1d2411c043afa624755fedb6b33dc5' 
  AND token = 'xgAsuiq9iAc2C2LdttCLNd8KSjTq8rfsV/9dZfAjpT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}