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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '960111fe6714c15ff2c29ac33c9df9eab52844ee7f42aecf1faa817c1f1cdffa' 
  AND token = 'pxoPcsvx5O2tB/05sm/2ZB/NG38ZkWwzEYEAy4wSVmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}