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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9569130be48e1071d7d01632eb648ff4d950ac4d1d18e8f86571bff5d8e5588d' 
  AND token = 'IilOM3SzPk3NuVqCa5L1fv3Iv0wVlYA0O6HK92jkScg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}