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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da751f454f9eaf517a43302243e0fffed2dee1eae083a4aeeadb9061af8fd469' 
  AND token = 'SAKk+GpZ/mZPUKHVM7Rr7hpWktsJ0AKqbpyI0Wn9Hxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}