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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '756a78df5c75a4e03430f892ffe04f157cf873cb0c8416ba926cd7e8eb22cc23' 
  AND token = 'hJ0A1aLVM8nlvTjmWX5eC73EyWnoEp4rlcbbr8OVx6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}