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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e33fe7e3f4ab525bc72d1f4068dedc85c8c8baec6d5e4232b7142b020cc1e971' 
  AND token = 'SYlnyRQiYiTkQeRytIDxYhaVRHnGrxKjNv2Qfw6AOpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}