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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f03ed8730f71d8addcef548b8c1f6675e7032c681c4c1bb0c907e4a773296a1' 
  AND token = 'F0W3L4Pw4sOwZT4jcZ+sXm6WLgjXoDYcgIlwsVFuPL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}