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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b16caaf4306312dee4bb39f3e31d2acc616ce81bc0930351c808f01f3b98e71' 
  AND token = 'R9LCq4XxietXjZt8z9jOkEehLeOGe3+HKArLjQmR8mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}