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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d0cfde78b79597e93772e6662054c76985ec582efb7c2e531d081b6f7d72a4e' 
  AND token = 'EbioBx4DhwmlqTjXB6TRH0T3yU7BCdsdhsIGGXXEges=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}