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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8888cacbb88512923cad573517a8a19e786d88178d2a701a48e56a2c61b7b586' 
  AND token = 'NfGvZCgQCun6Kp56x2DIBjy/b009Vx8w3zmRkTr5cp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}