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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3564d0cb162b19448936c2860e5e8675a3797d284938dcced7f19fe84989e97d' 
  AND token = 'uth/2wOkzDVkfXpNcUfcb+4Jp31/e5ng43Q2vKh8ePg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}