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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a2d2b0a3ed60f7f81abdb3b234de8d78f33a6f1b2ec38819686d393516f3623' 
  AND token = 'rq8B2IPM9PKDzhwy4/dCEk2z0Nx/I2t3OsqrQwFKgCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}