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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '915de5f55f91451f6a6643e026486c7f18e799fbf9d51dea94c770657a7dc07d' 
  AND token = 'er/TpW3yw3mw88KlNG6b0ehFNU7cpJ+jFzzTJkQ3wQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}