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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dde45ed34e01751466e999788d7a1ab8bc99b6e2e3ed9d1e959930319cf4b6e' 
  AND token = 'FXU9w3GQYCrax2cTuE7g0jGV+Rs8oWZM1BD6hQAvgV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}