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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '882b3d1181b30adfcf0c39594afe4c8923109747fce2cace9eb6e1b1ee90eb0d' 
  AND token = 'qYQdwjZq+IaDZFfZ1az/pKkCGzUIGDZQOI7eoXyjsW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}