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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '223ab18056410753936c2de016d0c326a8b1fee51095ea84a46bc1ce896a0ac1' 
  AND token = '9cKs9OpHOJbCxw72gnOK7C/i+W28zh/VGN4r2zackB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}