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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7ded083b9ac31a9b79cfc00675976d3e5df99e4c9e775de9b666fa0df9b3bab' 
  AND token = 'O550J3FjH/GhCFsoRWgPiyKmLbj9/32wKXFRe3sKaFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}