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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '652ed584f1127677c46c1be8a677abe43884a40de735a50f2eb931ee728a0cb8' 
  AND token = 'TabGI1px1Yhr6bW7myNvmnr/IMygiEcBwy7CRm0mUI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}