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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a49cbb8f6d03a812b55d6bdb1e407a202ea48d432b5b99b23581b725f6c85bc2' 
  AND token = 'hJAoK8EQOkaqdoAXt2dXj9OHN8Jl28VY2brKpUv/7Gc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}