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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '463ba17ab1462db03b6f866ab0d47f78c787a0b522783e92e030e44529bb320b' 
  AND token = 'YZtyY5RJzjVkFShmboG/MU1vMSjXFKMm4sWHFtl03oY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}