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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aa300ea62f60777a3cb2ee3ce35944da5d5b4923a1d4137883b1c8650729437' 
  AND token = 'dGISHNe6FmiX+srm8mU8zqQCr5RqfMpPrLGf/uQMmqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}