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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3440b2250727253ab2539046d9659527e77c906d7b3d87311fc9a59a4fb5aa0' 
  AND token = 'xFSbDIqlHaw4ORHJnwD86QE9qKN2uI9EVdO+rwx8uRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}