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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57be8604a6936350edfcdc7a9959cf494d228877e93d8b15bdb929340b07db5f' 
  AND token = 'kXoKkXaH4l+xcbPifHTy8Y7gKWUMKT9I62MXXjZvOGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}