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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44e28dd4d27acb5d935e61cd4ba92808284bde9579364dcfb85c82004d7f1c7c' 
  AND token = 'f78l0K47wmSnXC1uo0PQGX7cBUo8HvDZQiNUkYmMxeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}