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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc7dfca012c26edb5a9ec8fd06dccce775e7a23c2bb61eb78f964c939ab5d067' 
  AND token = '+k9vmkbGZMJ0CZ/bEMNj834ahvJNnQ8pWNDe8p15H0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}