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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e6a7d6663e11e434f2f96deb710914da25a39c2f6e178d8713fcafebd869742' 
  AND token = 'J5A2jJDIuegb0dG3aOJ50WVFlQyK3YI7FdGDym0XtHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}