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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9d451dbd11538f26704ade2a72211f6f4fe4f72d386c435e16b66c4de3edea3' 
  AND token = 'c53V2kxWm9hI24Ia6pRbU4o1nVsgpBJ0DCevyZQR0AA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}