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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a78d64c3976099078c2609e4e5792333bfb672b732933a77e386539baa552eb7' 
  AND token = 'ayITuiEkUwzYr7Y00RThmk0SGgbqeqN+vZWf1/t2Pw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}