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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8097dbc14e6ea9932b168b83c94f22dcd9a1c5bc0475d032c717d7b35499d10' 
  AND token = 'XWyn5ynm54toyd80PM1sCvLo4UeVPyBNfXih8sT/Oa8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}