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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43ea72ea0556284b95403a55c7a36402476dbd86e68435e5645d132068896d4c' 
  AND token = '9AKiHzSVvP7oe/fsnMNjakcTAEl93E9yT4NIksZI/UM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}