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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '165404e8fceb23290580a3ebde301c918411a54127b60e06307ea9f445b65ff8' 
  AND token = 'hQMXq4qOjYaK+knN7nlklV6NfO7N41A8RgTgLnzQ2nI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}