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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6537806ff062ef8d67dca397641a158ec412e0d802203d667360516a23c6ce7f' 
  AND token = 'PP7z/RecMMSr7Jnfs7TwnB04A0c5aEIA+lU4ex+bo0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}