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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a529a931fc7d2832a082f72f27b4701a85f716289ee5260afc3d6c9c27597137' 
  AND token = 'cxT/BWgSEUS0xx0rDA0fzCbNlF6eIySpqg0+5i8v6Lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}