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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0bb5236197b665f54503a81244d878f5f9c1934cb3d970c0c2bfd1f44523205' 
  AND token = 'vUbEnj4fkBdRYrZ/0uNsnhDnbKG3Mm8YSAieh6A6LMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}