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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a0b45f9497cd31efe31ca1b6e00b7454513946cce64df59e425f7520cae10c5' 
  AND token = 'mvJjUUYIYl6VBaY6EtDmIAPOVvBo9qH6ggf2NtGj8IU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}