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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00a294bcf26ca9ea8e2cb41ddc091f07950ff6c03ca834a1cc953e55287912f0' 
  AND token = 'p74WtF1tErPAAWJ4R+FwEZjC3wNtKrgB219Wan6ZvdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}