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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21371e050bc8d43dc2a62d3f56e86ff38bb5cbb185ce38ac3fcfe25637a9cab5' 
  AND token = 'aO87SnNmfKSomQ0N0AA3nn0LTHG+xZj/vUdCoSXRxSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}