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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '528ecb6f1a8ea0e3a3760dc2b53deb141f181ad61ed406da8aceb7f8bde4e758' 
  AND token = 'xU2H1ueKFJKUgdL0D+uF76UxyMN1IYp8QmzuH/Mx5kA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}