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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17648ad9e2d9a21b54526151b033564e2b4ac63b1747100cb5f0a2ca48d7908e' 
  AND token = 'duYQIdjb/q1umMO9+1tbJRAeIaTXixqwvtc3OMtxwqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}