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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '796b7fbcb61d62fcb551b17074054de930c5e2857be3f41b97dc55fa20bc7746' 
  AND token = 'gkW+NXNvG/otLUa2Ex2zSmfstbPbzrVD/Rdacr8GYgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}