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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f9f8b9d3dff468d048b6757d18eac4e8da61314a25f597e88f73315cecf22c3' 
  AND token = 'Ktz9bxECC2/rwCHATCp2XF1J1HJDxtsjXXQc/OEnxhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}