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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c680c746f02655dd87aec8d248d7c191c2decd8355681e2711861a4b6d348161' 
  AND token = 'sxtX0O+wnM6q9G0LDRdxM/ByM5hFC+a5bXNROl+nxWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}