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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a77bc0fe7a259e686aca375933628b43e84616f0f7f5fd315d5b5a208bfabdc1' 
  AND token = 'XcIGQMRWeNTqufd9p6OB6TXlxwIwEy9OK846wMvOdAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}