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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '462251bea464ec0868dfab66be9a20bd1d2a2f5ae433df12af5a666675414270' 
  AND token = 'pBGEkmWZkgL/8kQycFFgo8a5SaHAADFSGOV6dEpD/w4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}