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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9821f69ff42a937520a57aa8f4a33350a0621bb30eb3612a43998e175a59a2d7' 
  AND token = 'C4ld2Rz7mUA7k4uE1rGApirQ4nsRh4DNQmh3axy1Sxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}